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CREB, phosphorylated (Ser133) (cAMP Response Element Binding Protein) Blocking Peptide

Cat no: C7915-10A

CREB, phosphorylated (Ser133) (cAMP Response Element Binding Protein) Blocking Peptide

Transcription factor CREB binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity (1,2). Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1 (3

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SPECIFICATIONS

Catalog Number

C7915-10A

Size

100ug

Applications

ELISA, WB

Form

Supplied as a lyophilized powder.

Purity

Purified

References

1. Gonzalez, G.A. and Montminy, M.R. (1989) Cell 59, 675

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FC

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Hum

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Hosts

Mouse

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Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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