CREB (Ser133) Antibody

Cat no: 252530

Supplier: ABBIOTEC

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Description
Additional Information

As a dimer, CREB-1 (cAMP-responsive element-binding protein 1) binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters, to stimulate transcription. CREB-1 is activated by phosphorylayion on Ser-133 and Ser-142. Transcriptional activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 has been implicated in synchronization of circadian rhythmicity. It interacts with various proteins including TORC/CRTC, CREBBP, ARRB1.

Catalogue number:	252530
Reactivities:	Human, Mouse, Bovine, Chicken/Bird, Rabbit, Xenopus/Amphibian, Zebrafish/Fish
Applications:	Western Blot
Size:	0.1 ml
Accession:	P15337
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser133 of rat CREB.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	Cyclic AMP-responsive element-binding protein 1; cAMP response element-binding protein; CREB; CREB1; CREB-1