Established in 1996 from the diagnostic pre-treatment pleural effusion sampled shortly before death of a 49-year-old HIV+ homosexual man with primary effusion lymphoma (PEL) and previous history of Kaposis sarcoma; autopsy revealed involvement of serous membranes without formation of solid tumor mass; cells were described to be EBV+, HHV-8+ and to carry a BCL6 point mutation