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CRSP3 (CRSP130, CRSP133, Sur2, DRIP120, CRSP-130 Cofactor Required for Sp1 transcriptional activation, subunit 3, 130kD, DRIP130, DRIP-130, Vitamin D3 Receptor Interacting Protein)

CRSP3 (CRSP130, CRSP133, Sur2, DRIP120, CRSP-130 Cofactor Required for Sp1 transcriptional activation, subunit 3, 130kD, DRIP130, DRIP-130, Vitamin D3 Receptor Interacting Protein)

Cat no: C7506-02F

Supplier: United States Biological
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7506-02F
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: As reported
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: CRSP130, CRSP133, Sur2, DRIP120, CRSP-130 Cofactor Required for Sp1 transcriptional activation, subunit 3, 130kD, DRIP130, DRIP-130, Vitamin D3 Receptor Interacting Protein
Additional info: Specific for human CRSP 3 protein. Species Crossreactivity: Human. Other species not tested. Reactivity with mouse CRSP3 is expected owing to complete identity between this ortholog and human CRSP3 at the site to which the epitope maps.

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