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Products CRTH2/DP2 Receptor (C-Term) Polyclonal Antibody
| Catalogue number: | 10007002 |
| Hosts: | Rabbit |
| Applications: | Immunocytochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | CRTH2/DP2 protein amino acids 378-395 |
| P type: | Antibodies |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Prostaglandin D2 (PGD2) elicits its biological function through interaction with two distinct G protein-coupled receptors, DP1 and CRTH2/DP2. CRTH2 primarily couples to Gi or Gq subunits to mobilize Ca2+, induce cell migration, and up-regulate adhesion molecules. CRTH2 mRNA has been detected in various tissues including liver, lung, kidney, brain, heart, thymus, and spleen and in various cell lineages including both hematopoietic and non-hematopoietic cell lines. Human CRTH2 is 395 amino acids in length with an estimated molecular weight of 43 kDa. Cayman |
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