CSK (5F3) Antibody

Cat no: 253076

Supplier: ABBIOTEC

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Description
Additional Information

Csk (Carbo, Xenopus/Amphibian,y-terminal Src kinase) is a ubiquitously e, Xenopus/Amphibian,pressed nonreceptor tyrosine kinase. Csk negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carbo, Xenopus/Amphibian,y-terminal tyrosine. Phosphorylated carbo, Xenopus/Amphibian,y-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK. This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and e, Xenopus/Amphibian,clusive. The SFK carbo, Xenopus/Amphibian,y-terminal tyrosine is the only known physiological substrate of Csk. It is e, Xenopus/Amphibian,pressed in lungs and macrophages.

Catalogue number:	253076
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	P41240
Antigen:	Purified recombinant fragment of human CSK e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	5F3
Additional info:	Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK