Home  >  Products  >  Csk (C-Terminal Src kinase, C-Src Kinase, c-Src Tyrosine Kinase, Tyrosine Protein Kinase CSK, MGC117393, Protein-tyrosine Kinase CYL)
Csk (C-Terminal Src kinase, C-Src Kinase, c-Src Tyrosine Kinase, Tyrosine Protein Kinase CSK, MGC117393, Protein-tyrosine Kinase CYL)

Csk (C-Terminal Src kinase, C-Src Kinase, c-Src Tyrosine Kinase, Tyrosine Protein Kinase CSK, MGC117393, Protein-tyrosine Kinase CYL)

Cat no: C7945-02E

Supplier: United States Biological
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C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C-terminal tyrosine of Src family kinases thereby down-regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50kD in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:250-1:50 Weak non-specific band of 60kD is detected in human cell lines at lower antibody dilutions. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7945-02E
Reactivities: Mouse
Hosts: Mouse
Applications: Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: EC=2.7.10.2
Additional info: Recognizes human Csk. Species Crossreactivity: Mouse

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