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CST9, Recombinant, Human, aa29-159, His-tag (Cystatin 9, Cystatin-9, Cystatin-like Molecule, CLM)

Cat no: 029652

CST9, Recombinant, Human, aa29-159, His-tag (Cystatin 9, Cystatin-9, Cystatin-like Molecule, CLM)

CST9, is a member of the CRES (cystatin-related epididymal spermatogenic) subfamily. The CRES (cystatin-related epididymal spermatogenic) protein defines a newsubgroup in the family 2 cystatins of the cystatin superfamily. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. CST9 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. CST9 is thought to play a role in hematopoietic differentiation or inflammation. It has also been shown to be upregulated by LPS in some cancer cell lines, such as promyelocytic leukemia (HL-60) and myelomonocytic leukemia.\n\nSource:\nRecombinant corresponding to aa29-159 from human CST9, fused to His-tag at N-terminal expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MWCSEEEMGG NNKIVQDPMF LATVEFALNT FNVQSKEEHA YRLLRVLSSW REDSMDRKWR GKMVFSMNLQ LRQTVCRKFE DDIDNCPFQE SLELNNVRQG ISFPQVHSCG CCMGCGVGTG AADKAIPRDK GK\n\nMolecular Weight:\n~17.2kD\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

029652

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Sun H., et al. (2003) Biochem Biophys Res Commun. 301:176-182. 2. Von Horsten H H., et al. (2007) J Biol Chem. 282:32912-32923.

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