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CTNND1, CT (Catenin delta-1, Cadherin-associated Src Substrate, CAS, p120 Catenin, p120(ctn), p120(cas), KIAA0384)

Cat no: C2069-54L

CTNND1, CT (Catenin delta-1, Cadherin-associated Src Substrate, CAS, p120 Catenin, p120(ctn), p120(cas), KIAA0384)

Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules. Delta-1-catenin is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor.\n\nApplications: \nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Formalin-fixed, paraffin-embedded): 1:15 \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2069-54L

Size

50ul

Applications

IHC

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in10mM PBS, pH 7.4, BSA, sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Additional Info

Recognizes human P120.

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Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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