Home  >  Products  >  CTRP13, globular domain, Recombinant, Human (His) (C1qTNF-related Protein 13, C1QTNF13, C1QL3, C1ql, K100, Complement C1q Tumor Necrosis Factor-related Protein 13)
CTRP13, globular domain, Recombinant, Human (His) (C1qTNF-related Protein 13, C1QTNF13, C1QL3, C1ql, K100, Complement C1q Tumor Necrosis Factor-related Protein 13)

CTRP13, globular domain, Recombinant, Human (His) (C1qTNF-related Protein 13, C1QTNF13, C1QL3, C1ql, K100, Complement C1q Tumor Necrosis Factor-related Protein 13)

Cat no: 044687

Supplier: United States Biological
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CTRP13 (C1qTNF-related protein 13) belongs to a highly conserved family of adiponectin paralogs. CTRP13 is an adipokine that promotes glucose uptake in adipocytes, myotubes and hepatocytes via activation of the AMPK signaling pathway. CTRP13 ameliorates lipid-induced insulin resistance in hepatocytes through suppression of the SAPK/JNK stress signaling that impairs the insulin signaling pathway. CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase. CTRP13 has insulin-sensitizing activity and is important in glucose homeostasis. CTRP13 is preferentially expressed by adipose tissue and the brain in mice and predominantly by adipose tissue in humans. Sequence: The globular domain of human CTRP13 (aa 120-255) is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 1 year after receipt when stored at -20 degrees C. Working aliquots are stable for up to 6 months when stored at -20 degrees C.
Catalogue number: 044687
Size: 10ug
Form: Supplied as a lyophilized powder from a 0.2um-filtered solution in 50mM TRIS-Cl, pH 8.2, 150mM NaCl.
Purity: >95% (SDS-PAGE)
Alternative names: C1qTNF-related Protein 13, C1QTNF13, C1QL3, C1ql, K100, Complement C1q Tumor Necrosis Factor-related Protein 13

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