Home  >  Products  >  CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5, C1QTNF5, DKFZP586B0621, FLJ30570, LORD)
CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5, C1QTNF5, DKFZP586B0621, FLJ30570, LORD)

CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5, C1QTNF5, DKFZP586B0621, FLJ30570, LORD)

Cat no: C7948-25D5

Supplier: United States Biological
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Mutation to CTRP5 causes it to be retained in the endoplasmic reticulum, and can lead to late-onset retinal degeneration (LORD) and long anterior lens zonules. CTRPs are often highly modified post-translationally, so whereas the predicted molecular weight for CTRP5 is 25kD, AHP1176 detects a single band at 40kD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7948-25D5
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Complement C1q Tumor Necrosis Factor Related Protein 5 Precursor
References: 1. Shu, X. et al. (2006) Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5. Hum. Mol. Genet. 15: 1680-1689. 2. Ayyagari, R. et al. (2005) Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. Invest. Ophthalmol. Vis. Sci. 46: 3363-3371.
Additional info: Recognizes an epitope within human C1q and TNF related protein 5 (CTRP5). Species sequence homology: mouse and rat.

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