Cullin 2 (CUL -)

Cat no: C7949-10D

Supplier: United States Biological

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Description
Additional Information

Cullins (1, 2, 3, 4a, 5 and 7) are a family of proteins that assemble a large number of ubiquitin ligases to catalyse polyubiquitiation, as well as binding to various specific factors to recruit substrates. Cullin 2 (CUL 2) is a component of E3 ubiquitin ligase complexes which controls the proteolysis of G1 cell cycle regulatory proteins. It forms a complex with an inactive transcriptional elongation complex formed by three subunits elongain C, elongain B and VHL. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:100 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C7949-10D
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	1mg
Form:	Supplied as a liquid in PBS, pH 7.2.
P type:	Pab
Purity:	Purified by Protein G affinity chromatography.
References:	Michel, J.J. & Xiong, Y. (1998) Cell Growth Differ. 9,435-449. Liakopoulos, D. et al. (1999) Proc. Natl. Acad. Sci. USA 96,5510-5515.
Additional info:	Recognizes human CUL 2

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Cullin 2 (CUL -)

Cat no: C7949-10D

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