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Curcumin-d6

Curcumin-d6

Cat no: 007125

Supplier: United States Biological
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Labeled Curcumin. A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IkB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Melting Point: As Reported Solubility: As Reported Method for determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: As Reported Elemental Analysis: As Reported Normalized Intensity: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:
Catalogue number: 007125
Size: 5mg
Form: As Reported
Purity: ~90%
Alternative names: (1E,6E)-
References: 1. Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), 2. Tu, B., et al.: J .Cell Biol., 164, 341 (2004), 3. Xu, G., et al.: Biochemistry, 44, 9817

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