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CX3CL1, Soluble, Recombinant, Human (Fractalkine)

Cat no: 044716

CX3CL1, Soluble, Recombinant, Human (Fractalkine)

CX3CL1 (fractalkine) is expressed on TNF-alpha and IL-1 activated endothelial cells (ECs). CX3CL1 can exist in 2 forms: as membrane-anchored or as a shed 95kD glycoprotein. The soluble CX3CL1 has potent chemoattractant activity for T cells and monocytes, and the cell surfacebound protein, which is induced on activated primary endothelial cells, promotes strong adhesion of those leukocytes. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.\n\nBiological Activity:\nChemotaxis effect of soluble recombinant human CX3CL1 in THP-1 cells.\n\nSequence:\nSignal peptide and extracellular domain of human CX3CL1 (aa 1-339) are fused at the C-terminus to a FLAG(R)-tag.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nWorking aliquots are stable for up to 3 months when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044716

Size

10ug

Form

Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.

Purity

>90% (SDS-PAGE)

Alternative Names

Fractalkine

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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