Home  >  Products  >  CX3CR1, NT (CX3C Chemokine Receptor 1, C-X3-C CKR-1, Beta Chemokine Receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine Receptor, G-protein Coupled Receptor 13, V28, CMKBRL1, GPR13)
CX3CR1, NT (CX3C Chemokine Receptor 1, C-X3-C CKR-1, Beta Chemokine Receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine Receptor, G-protein Coupled Receptor 13, V28, CMKBRL1, GPR13)

CX3CR1, NT (CX3C Chemokine Receptor 1, C-X3-C CKR-1, Beta Chemokine Receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine Receptor, G-protein Coupled Receptor 13, V28, CMKBRL1, GPR13)

Cat no: C8299-01P

Supplier: United States Biological
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CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C8299-01P
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Raport, CJ. et al. Gene 163, 295 (1995). 2. Combadiere, C. et al. DNA Cell Biol 14, 673 (1995). 3. Combadiere, C. et al. Biochem Biophys Res Commun 253, 728 (1998). 4. Harrison, JK. et al. Neurosci Lett 169, 85 (1994). 5. Imai, T. et al. Cell 91, 521 (1997). 6. Combadiere, C. et al. J Biol Chem 273, 23799 (1998).
Additional info: Recognizes human CX3CR1.

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