The murine homolog of ENA-78 is called LIX. LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70aa, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR� motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 7.6kD protein consisting ofaa 9-78 of the full length LIX protein (93aa).
Source:
Recombinant protein corresponding to mouse LIX, expressed in E.coli.
Biological Activity:
Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml.
Endotoxin:
<0.1ng/ug (1EU/ug)
AA Sequence:
TELRCVCLTV TPKINPKLIA NLEVIPAGPQ CPTVEVIAKL KNQKEVCLDP EAPVIKKIIQ KILGSDKKKA
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Quick Search
Products 
