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CXCR-3 (H202) pAb

CXCR-3 (H202) pAb

Cat no: BS2693

Supplier: Bioworld Technology, Inc.
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The CXC or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemo-attractants for neutrophils. The CXC family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 or SDF-1. Receptors for the CXC family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (variously referred to as LESTR or CXCR-4). CXCR-3, also known as IP-10/Mig receptor, mediates Ca++ mobilization and chemotaxis in response to the CXC chemo-kines IP-10 and Mig. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes.
Catalogue number: BS2693
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P49682
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 280-320 of Human CXCR-3.
Species: CXCR-3 (H202) pAb detects endogenous levels of CXCR-3 protein.
Molecular weight: ~ 41 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183; GPR9; CXCR3
Additional info: For research use only, not for use in diagnostic procedure.

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