CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)

Mouse spleen cells\n\nCellular Localization: Cell Membrane\n\nPositive Control: Mouse spleen cells\n\nApplications: \nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C8375-01B

Size

100ug

Applications

ELISA, ICC, IHC, WB

Hosts

Goat

Reactivities

Mouse

Form

PBS, 1mg/ml BSA, pH7.2

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

This product has been used in:Bieniasz PD et al. Murine CXCR-4 is a functional coreceptor for T-cell-tropic and dual-tropic strains of human immunodeficiency virus type 1. J Virol 717097-100 (1997). <PUBMED:9261443>Heesen M et al. Cloning of the mouse fusin gene, homologue to a human HIV-1 co-factor. J Immunol 157:5455-60 (1996). <PUBMED:8955194>\n3. Belmadani, A., et al. The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors. J. Neurosci. 25(16):3995-4003, 2005.\n4. Nishiumi, F., et al. The mode and molecular mechanisms of the migration of presumptive PGC in the endoderm cell mass of Xenopus embryos. Dev. Growth Differ. 47(1):37-48, 2005.\n5. Tran, P.B., et al. Chemokine recpetors are expressed widely by embryonic and adult neural progenitor cells. J. Neurosci. Res. 76(1):20-34, 2004.\n6. Kayali, A.G., et al. The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas. J. Cell Biol. 163(4):859-869, 2003.

Additional Info

This antibody binds to CXCR 4 receptor on mouse spleen leukocytes as determined by immunocytochemistry. Species Crossreactivity: Crossreacts with Mouse.

Alternative Names

CD184, Chemokine CXC Motif Receptor 4, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3, NPYY3R, Probable G protein coupled receptor lcr1 homolog, WHIM