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CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)

Cat no: C8375-01E


Supplier: United States Biological
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CXCR4, also termed Fusin, LESTR, or HUMSTR is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a coreceptor for X4 HIV-1 entry into CD4+ cells. CXCR4 is expressed predominantly on na
Catalogue number: C8375-01E
Reactivities: Human, Feline
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 5% trehalose.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography.
Alternative names: CD184, Chemokine CXC Motif Receptor 4, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3, NPYY3R, Probable G protein coupled receptor lcr1 homolog, WHIM
References: 1. Zhang, Y., et al., Stem Cells 22: 1015-1029 (2004).
Additional info: Recognizes human CXCR4 (fusin) transfected cells and not with the parent cell line by Flow Cytometry. Shows no crossreactivity with other chemokine receptors. Antibody will neutralize human cell surface CXCR4 mediated SDF/PBSF response using human cultured lymphocytes in a chemotaxis assay. Species Crossreactivity: Human and Feline. Does not crossreact with Rat.

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