This antibody may be used to examine the biological behavior of tumors. Cyclins are proteins that vary in abundance and are associated with and activate cyclin dependent kinases at different stages of the cell cycle. Cyclin A is detectable in S phase increasing during progression into G2 phase. Increased expression of various cyclins have been noted in some human cancers.
Cellular Localization: Nuclear
Positive Control: Tonsil
Applications:
Suitable for use in Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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