Cyclin D1 Antibody

Cat no: 250491

Supplier: ABBIOTEC

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Description
Additional Information

Cyclin-D1 (BCL-1) comple, Xenopus/Amphibian,es with CDK4 and CDK6 serine/threonine protein kinases to impart substrate specificity. Cyclin-D1 is essential for G1/S phase transition. Following DNA damage, Cyclin-D1 is phosphorylated at Thr-286 by MAP kinases, leading to its FB, Xenopus/Amphibian,O31-mediated ubiquitination and subsequent degradation. Chromosomal aberrations of CCND1 lead to various neoplastic and proliferative disorders.

Catalogue number:	250491
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P25322
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the central region of rodent Cyclin-D1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene; BCL-1 oncogene; BCL1; PRAD1; B-cell lymphoma 1 protein; CCND1; Cyl-1