Cyclin D2 Antibody

Cat no: 251517

Supplier: ABBIOTEC

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Description
Additional Information

Cyclin D2 is the regulatory component of the cyclin D2-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F comple, Xenopus/Amphibian, and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 comple, Xenopus/Amphibian,es are major integrators of various mitogenenic and antimitogenic signals.

Catalogue number:	251517
Reactivities:	Human, Mouse, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P30279
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cyclin D2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Cyclin D2; G1/S-specific cyclin-D2; CCND2