Cyclin D2

Cat no: C8454-12E

Supplier: United States Biological

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Additional Information

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk), which control transition at different specific phases of the cell cycle. In mammalian cells, cyclin D2 plays a critical role in G1 to S transition and is a putative proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk4 and/or cdk6. Applications: Suitable for use in Immunofluorescence, Immunoblotting, Immunoprecipitation, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C8454-12E
Reactivities:	Human, Mouse
Hosts:	Mouse
Applications:	Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Size:	5ml
Form:	Supplied as a liquid in 0.09% sodium azide.
P type:	Mab
Isotype:	IgG2a
Purity:	Supernatant
Additional info:	Recognizes human Cyclin D2. Known to interact with Cdk4 in the G1 phase of the cell cycle. Does not cross-react with cyclin D1 and cyclin D3. Species Crossreactivity: mouse.

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Cyclin D2

Cat no: C8454-12E

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