Home  >  Products  >  Cyclin Dependent Kinase 2-associated Protein 1 (CDK2 Associated Protein 1, CDK2-associated Protein 1, CDK2AP1, Deleted in Oral Cancer 1, DOC 1, DOC1, DOC-1, DOC 1-related Protein, DOC 1R, DOC1R, DOC-1R, Putative Oral Cancer Suppressor)

Cyclin Dependent Kinase 2-associated Protein 1 (CDK2 Associated Protein 1, CDK2-associated Protein 1, CDK2AP1, Deleted in Oral Cancer 1, DOC 1, DOC1, DOC-1, DOC 1-related Protein, DOC 1R, DOC1R, DOC-1R, Putative Oral Cancer Suppressor)

Cat no: C8471-40


Supplier: United States Biological
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The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes Applications: Suitable for use in Western Blot, Dot Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunocytochemistry: 2-100ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C8471-40
Reactivities: Human
Hosts: Mouse
Applications: Immunocytochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human Cyclin Dependent Kinase 2-associated Protein 1.

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