Cyclin-dependent Kinase 5 (Cdk5) (epitope b)

Cat no: C2575-07C

Supplier: United States Biological

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Description
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Cyclin-dependent kinase 5 (Cdk5) belongs to the Ser/Thr protein kinase family. It is ubiquitously expressed in both cycling and noncycling cells but its activity is detected almost exclusively in brain extracts. Cdk5 is activated by p35 protein which is only expressed in the brain. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:25 Western Blot: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C2575-07C
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	1mg
Form:	Supplied as a liquid in PBS, pH 7.2.
P type:	Pab
Purity:	Purified by Protein G affinity chromatography.
References:	Pines, J. (1995) Biochem. J. 308,697-711. Maccioni, R. et al. (2001) Eur. J. Biochem. 268,1518-1527. O'Hare, M.J. et al. (2005) J. Neurosci. 25,8954-8966. Angelo, M. et al. (2006) J. Neurochem. 99, 353-370.
Additional info:	Recognizes human Cdk5

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Cyclin-dependent Kinase 5 (Cdk5) (epitope b)

Cat no: C2575-07C

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