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Cyclin Dependent Kinase Inhibitor 2C (CDKN2C) Recombinant, Human

Cat no: C8471-68

Cyclin Dependent Kinase Inhibitor 2C (CDKN2C) Recombinant, Human

This protein is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of the gene encoding this protein was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. \n\nSpecies: Homo sapiens\n\nSource: E. coli\n\nPrimary Sequence (aa): 168\n\nDomain (aa): Full-length\n\nTag/Fusion Partner: T7 Tag\n\nApplications: Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested.\n\nQuality Control: SDS-PAGE Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. \n\nImportant note: This recombinant enzyme has NOT been tested with regard to biological activity.

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SPECIFICATIONS

Catalog Number

C8471-68

Size

50ug

Applications

ELISA

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added.

Purity

Highly purified

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