Home  >  Products  >  Cyclooxygenase-2 (PTGS2, Prostaglandin G/H Synthase 2, COX-2, PHS II, Prostaglandin H2 Synthase 2, PGH Synthase 2, PGHS-2, Prostaglandin-endoperoxide Synthase 2)
Cyclooxygenase-2 (PTGS2, Prostaglandin G/H Synthase 2, COX-2, PHS II, Prostaglandin H2 Synthase 2, PGH Synthase 2, PGHS-2, Prostaglandin-endoperoxide Synthase 2)

Cyclooxygenase-2 (PTGS2, Prostaglandin G/H Synthase 2, COX-2, PHS II, Prostaglandin H2 Synthase 2, PGH Synthase 2, PGHS-2, Prostaglandin-endoperoxide Synthase 2)

Cat no: C7904-83L

Supplier: United States Biological
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Prostaglandin-endoperoxide synthase (fatty acid cyclooxygenase; PGH synthase; Cox-2) is a key enzyme in prostaglandin biosynthesis. The first rate-limiting step in the conversion of arachidonic acid to prostaglandins is catalyzed by Cox-1 and Cox-2. The cyclooxygenase activity of Cox-2 is inhibited by nonsteroidal antiinflammatory drugs such as aspirin and endomethacin. It is a mitogen-inducible gene (unlike Cox-1, which is a house-keeping gene), and this means it probably is a primary mediator of the inflammatory response. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7904-83L
Reactivities: Human
Hosts: Goat
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in TBS, pH 7.4, 50% glycerol, 0.1% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human PTGS2. Species sequence homology: Mouse, rat and sheep.

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