Cyclophilin F, aa30-207, Recombinant, Human (Peptidyl Prolyl Cis Trans Isomerase F, PPIASE)

Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.\n\nSequence of amino acids:\nMGSSHHHHHH SSGLVPRGSH CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS \nKSGRTSKKIV ITDCGQLS\n\nMolecular Weight: 21kD (198aa) \n\nEndotoxin: (same/less than)1.0 EU/ug of protein (determined by LAL method)\n\nStorage and Stability:\nFor long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

C8855-61A

Size

100ug

Form

Supplied as a liquid in 20mM Tris pH 7.5, 1mM DTT, 10% glycerol.

Purity

(same/more than) 95% by SDS PAGE. Recombinant, Human PPIF protein was expressed in E. coli and purified by using conventional chromatography techniques.

References

1. Bergsma DJ., et al. (1991) J Biol Chem. 266(34):23204-14. 2. Bowles KR., et al. (2000) Genomics 67(2):109-27.