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CYP2D6 (A300) Peptide

Cat no: BS5684P

CYP2D6 (A300) Peptide

Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx, and stomach and, especially, to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs.

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SPECIFICATIONS

Catalog Number

BS5684P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide CYP2D6 (A300). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P10635

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5684 CYP2D6 (A300) pAb.

Alternative Names

Cytochrome P450 2D6; CYPIID6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase; CYP2DL1

SUPPLIER INFO

Bioworld Technology, Inc.

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