CYP2E1 Peptide

Cat no: BS5686P

Supplier: Bioworld Technology, Inc.

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Cytochrome P450 2E1 (CYP2E1) localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous levels of substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. CYP2E1 plays an important role in alcohol metabolism and participates in the metabolic activation of various carcinogens. Chronic ethanol consumption results in the induction of hepatic CYP2E1 in humans, which may play an important role in the pathogenesis of alcoholic liver disease. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Catalogue number:	BS5686P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P05181
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CYP2E1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; Cytochrome P450-J; Cytochrome P450 2E1, N-terminally processed; CYP2E
Additional info:	This peptide can be used with studies using BS5686 CYP2E1 pAb.

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CYP2E1 Peptide

Cat no: BS5686P

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