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CYP2J2 Peptide

CYP2J2 Peptide

Cat no: BS5687P

Supplier: Bioworld Technology, Inc.
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CYP2J2 (cytochrome P450 2J2), also known as CPJ2, is a member of the cytochrome P450 protein superfamily. Localized to the ER (endoplasmic reticulum) and microsomal membranes, CYP2J2 is one of three cytochrome P450 enzymes that are responsible for metabolizing arachidonic acid to epoxyeicosatrienoic acids. Functioning via an NADPH-dependent olefin epoxidation, CYP2J2 epoxidizes endogenous cardiac arachidonic acid pools to four different isoforms of epoxyeicosatrienoic acid, all of which are important regulators of cardiovascular homeostasis and vascular tone. CYP2J2 is highly expressed in the heart with low levels of expression found in the liver, colon and kidneys. Up-regulation of CYP2J2 by a c-Jun responsive pathway is thought to promote the neoplastic phenotype of certain carcinoma cells, implicating CYP2J2 in carcinogenesis.
Catalogue number: BS5687P
Applications: Block/Neutralize/Inhibit
Swiss prot: P51589
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CYP2J2. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cytochrome P450 2J2; Arachidonic acid epoxygenase; CYPIIJ2
Additional info: This peptide can be used with studies using BS5687 CYP2J2 pAb.

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