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SPECIFICATIONS
Price
323.00 USD
Catalog Number
CAC07575
Size
100 micro g
Applications
IF, WB
Hosts
Rabbit
Conjugates
Unconj
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Target
CYP4F11
Clonality
Polyclonal
Storage Temp
Aliquot and store at -20 degrees C. Minimize freezing and thawing.
Research Area
For research use only. Not for diagnostic procedures.
Shipping Temp
Blue ice
Additional Info
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine.
Alternative Names
Phylloquinone omega-hydroxylase CYP4F11,3-hydroxy fatty acids omega-hydroxylase CYP4F11,Cytochrome P450 4F11,CYPIVF11,CYP4F11
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