Home  >  Products  >  CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC)
CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC)

CYPC (Peptidyl-prolyl Cis-trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC)

Cat no: C8855-19

Supplier: United States Biological
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Cyclophilin C (CyPC, also Rotamase C and peptidyl-prolyl cis-trans isomerase C) is a 17-23kD member of the cyclophilin-type PPIase family of molecules. It is known to be a Mg2+-dependent intracellular enzyme that can degrade DNA into 50 kb fragments. It also has the potential to interact extracellularly with OPN and activate CD147/EMMPRIN. Human CyPC is 212aa in length. It contains one cyclophilin type PPIase domain (aa41-198). Over aa31-182, human CyPC shares 95aa identity with mouse CyPC, 59%, 79%, 58% aa identity with human CyPA, B and D, respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C8855-19
Reactivities: Human
Hosts: Sheep
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS to 200ug/ml.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Cyclophilin C. Species sequence homology: recombinant human Cyclophilin A, rhCyclophilin A-Like 4, rhCyclophilin B, rhCyclophilin E and rhCyclophilin F (1%).

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