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CysLTR2 (H324) pAb

CysLTR2 (H324) pAb

Cat no: BS2772


Supplier: Bioworld Technology, Inc.
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Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 Receptor and CysLT2 Receptor, to induce potent bronchoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 Receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 Receptor. The effects of the CysLT Receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.
Catalogue number: BS2772
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: Q9NS75
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 292-343 of Human CysLTR2.
Species: CysLTR2 (H324) pAb detects endogenous levels of CysLTR2 protein.
Molecular weight: ~ 40 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Cysteinyl leukotriene receptor 2; CysLTR2; G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321; CYSLTR2; CYSLT2; CYSLT2R; PSEC0146
Additional info: For research use only, not for use in diagnostic procedure.

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