Home  >  Products  >  Cystatin 8 (CST8, Cystatin-Related Epididymal Specific, CRES, Cystatin-8, Cystatin-related Epididymal Spermatogenic Protein CST8, Cystatin-Related Epididymal-Specific)

Cystatin 8 (CST8, Cystatin-Related Epididymal Specific, CRES, Cystatin-8, Cystatin-related Epididymal Spermatogenic Protein CST8, Cystatin-Related Epididymal-Specific)

Cat no: C8950-28


Supplier: United States Biological
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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing identified in mouse is suggested in human based on EST evidence but the full-length nature of putative variants has not been determined. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:64,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C8950-28
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: CRES, Cystatin-8, Cystatin-related epididymal spermatogenic protein CST8, cystatin-related epididymal-specific, cystatin-related epididymal spermatogenic protein, cystatin 8 (cystatin-related epididymal specific), cystatin 8, CRES
References: 1. Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, DeKosky ST, Lemoine Y, Iwatsubo T, Wavrant-Devri
Additional info: Recognizes Cystatin 8. Species sequence homology: human.

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