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Cysteine-rich, Angiogenic Inducer 61 (CYR61)

Cysteine-rich, Angiogenic Inducer 61 (CYR61)

Cat no: C9018-01E

Supplier: United States Biological
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Cysteine-rich angiogenic inducer 61, also known as CYR61, is a growth factor-inducible, immediate-early gene that has multifaceted activities in various cancers. CYR61 is a secreted heparin-binding extracellular matrix-associated protein whose activities include the promotion of adhesion and chemotaxis, and the stimulation of fibroblast and endothelial cell growth. CYR61 induces angiogenesis and promotes tumor growth and is expressed in dermal fibroblasts during cutaneous wound healing. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:250-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C9018-01E
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied in liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1.Tong X., et al. (2004) Oncogene. 23(28):4847-55 2.Latinkic BV., et al. (2003) Development. 130(11):2429-41 3.Grzeszkiewicz TM., et al. (2001) J Biol Chem. 276(24):21943-50
Additional info: Recognizes human CYR61.

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