Home  >  Products  >  CYT19 (Arsenite Methyltransferase, Methylarsonite Methyltransferase, S-adenosyl-L-methionine:arsenic(III) Methyltransferase, AS3MT)

CYT19 (Arsenite Methyltransferase, Methylarsonite Methyltransferase, S-adenosyl-L-methionine:arsenic(III) Methyltransferase, AS3MT)

Cat no: C9097-24D2


Supplier: United States Biological
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Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO3H2, which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me2As(O)-OH. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C9097-24D2
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Lin S, Shi Q, Nix FB, Styblo M, Beck MA, Herbin-Davis KM, Hall LL, Simeonsson JB, Thomas DJ. A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol. J Biol Chem. 2002 Mar 29;277(13):10795-803. Epub 2002 Jan 14. PMID: 11790780.
Additional info: Recognizes Cyt19. Species sequence homology: human.

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