CYTIP (PSCDBP, Cytohesin-interacting Protein, Cytohesin Binder and Regulator, CYBR, Cytohesin-associated Scaffolding Protein, CASP, Cytohesin-binding Protein HE, Cbp HE, Pleckstrin Homology Sec7 and Coiled-coil Domains-binding Protein)

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications have not been tested. \n\nRecommended Dilutions: \nPeptide ELISA Titer: 1:16,000\nWestern Blot: 1-3ug/ml detects ~38kD band observed in lysates of cell line MOLT4 (calculated MW of 40.0kD according to NP_004279.3)\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C9096-05D

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by peptide affinity chromatography.

Isotype

IgG

References

1. The goat polyclonal antibody used in this paper was manufactured by us:O'Brien M, Morrison JJ, Smith TJ.Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 gene expression in human myometrium at labor.Reprod Sci. 2008 Apr;15(4):382-93.

Additional Info

Recognizes human CYTIP.

Alternative Names

pleckstrin homology, Sec7 and coiled/coil domains, binding protein, pleckstrin homology, Sec7 and coiled-coil domains, binding protein, cytohesin binder and regulator, cytohesin 1 interacting protein, pleckstrin homology, Sec7, and coiled-coil domains protein-binding protein, cytohesin-1 interacting protein, cytohesin binding protein HE, CASP, B3-1, HE, pleckstrin homology, Sec7 and coiled/coil domains, binding protein, CYBR, PSCDBP, CYTIP