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Cytochrome P450 2A3 cDNA Probe, Human, BioGenomics(TM)

Cat no: C9095-15Q

Cytochrome P450 2A3 cDNA Probe, Human, BioGenomics(TM)

Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.\n\nSize of the cDNA:\n0.57Kb\n\nApplications:\nSuitable for use for synthesis, by standard random priming or nick translation techniques, of radiolabeled probes for investigations of P450 2A3 gene expression. Other applications not tested.\n\nOptimum dilutions to be determined by researcher.\n\nStorage and Stability:\nCan be stored for at least one year at -70 degrees C. Avoid repeated freeze/thaw cycles.

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SPECIFICATIONS

Catalog Number

C9095-15Q

Size

1ug

Form

Supplied in TE buffer.

References

1. Nebert, D.W., and Gonzalez, F.J., (1987) Ann Rev Biochem. 56: 945.2. Guengerich, F.P., (1988) Cancer Research 48: 2946.3. Nebert, D.W. et al. (1989) DNA. 8:1.

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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