Cytomegalovirus EXT-2, Strain AD169 (CMV)

Cytomegalovirus (CMV) antigen is considered one of the most common viral infections in man. The virus rarely causes disease, but may persist as a latent or chronic infection of the salivary glands, renal tubules, cervix and leukocytes. CMV infections are frequent and occasionally severe in children or adults with congenital or acquired defects of cellular immunity, such as patients with AIDS, cancer and recipients of organ transplants. The transmission of CMV via transfused blood may account for the majority of the CMV infections in organ transplant recipients, neonates and heart surgery patients. Medical conditions resulting from Cytomegalovirus infections include: interstitial pneumonia, mononucleosis (heterophile negative), congenital defects, abortion, mental retardation, blindness and deafness.\n\nThe CMV EXT2 process for C9100-03E is designed to select the CMV glycoprotein antigens of the infected fibroblast cells. This enriches for the antigens found on the surface of the cell that react with IgG antibodies.\n\nSource:\nCytomegalovirus, Strain AD169, propagated in human fibroblast cells.\n\nInactivation:\nUltraviolet light \n\nApplications:\nSuitable for use in solid phase immunoassays. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.

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