Home  >  Products  >  Daxx, ID (Death Domain-associated Protein 6, Daxx, hDaxx, Fas Death Domain-associated Protein, ETS1 associated Protein 1, EAP1, BING2, DAP6)
Daxx, ID (Death Domain-associated Protein 6, Daxx, hDaxx, Fas Death Domain-associated Protein, ETS1 associated Protein 1, EAP1, BING2, DAP6)

Daxx, ID (Death Domain-associated Protein 6, Daxx, hDaxx, Fas Death Domain-associated Protein, ETS1 associated Protein 1, EAP1, BING2, DAP6)

Cat no: D1150-06A

Supplier: United States Biological
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Death associated protein 6 (daxx) is found in the major histocompatibility complex class I region of the zebrafish. Its role in zebrafish is not well characterized in literature. One study has found a high degree of linkage conservation between the zebrafish class I and mammalian class II regions. In humans, daxx is thought to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6. Daxx-mediated apoptosis may be blocked by HSPB1/HSP27 through preventing interaction with TNFRSF6 and MAP3K5. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: D1150-06P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D1150-06A
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.1% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Sultmann, H et al (2000) Scand. J. Immunol. 51(6):577-585 2. Hollenbach, AD et al (2002) J. Cell Sci. 115:3319-3330
Additional info: Recognizes zebrafish Daxx.

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