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DCN pAb

DCN pAb

Cat no: BS6582

Supplier: Bioworld Technology, Inc.
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Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as FibroPVRL1 and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF(beta) and is a direct or indirect negative modulator of TGF(beta) synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-g and TNFa may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. The human Decorin gene maps to chromosome 12q21.33 and encodes a 359 amino acid protein.
Catalogue number: BS6582
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P07585
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human DCN.
Species: DCN pAb detects endogenous levels of DCN protein.
Molecular weight: 8,19,23,27,42kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CSCD; DCN; DCN protein; Decorin
Additional info: For research use only, not for use in diagnostic procedure.

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