DCP2 Antibody

Cat no: 252209

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

mRNA-decapping enzyme 2 (DCP2) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 plays a role in replication-dependent histone mRNA degradation. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. DCP2 has higher activity towards mRNAs that lack a poly(A) tail, and has no activity towards a cap structure lacking a RNA moiety.

Catalogue number:	252209
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q8IU60
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DCP2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	mRNA-decapping enzyme 2; hDpc; Nucleoside diphosphate-linked moiety , Xenopus/Amphibian, motif 20; Nudi, Xenopus/Amphibian, motif 20; DCP2; NUDT20