Home  >  Products  >  Desmoglein 1 (Desmosomal Glycoprotein 1, DG1, DGI, DSG1, DSG, CDHF4, Pemphigus Foliaceus Antigen, PPKS1, SPPK1)
Desmoglein 1 (Desmosomal Glycoprotein 1, DG1, DGI, DSG1, DSG, CDHF4, Pemphigus Foliaceus Antigen, PPKS1, SPPK1)

Desmoglein 1 (Desmosomal Glycoprotein 1, DG1, DGI, DSG1, DSG, CDHF4, Pemphigus Foliaceus Antigen, PPKS1, SPPK1)

Cat no: D3221-82E

Supplier: United States Biological
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Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D3221-82E
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: pemphigus foliaceus antigen, desmosomal glycoprotein 1, DSG, DG1, CDHF4, desmoglein 1, DSG1
References: 1. Nilles L.A., Parry D.A., Powers E.E., Angst B.D., Wagner R.M., Green K.J Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome J. Cell Sci. 1991 Aug 99 ( Pt 4): 809-21
Additional info: Recognizes Desmoglein 1. Species sequence homology: human.

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