DGCR8 Antibody

Cat no: 252193

Supplier: ABBIOTEC

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Description
Additional Information

Microprocessor comple, Xenopus/Amphibian, subunit DGCR8 (DGCR8) is a component of the microprocessor comple, Xenopus/Amphibian, that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor comple, Xenopus/Amphibian,, DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Catalogue number:	252193
Reactivities:	Human, Rabbit
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q8WYQ5
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of DGCR8.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Microprocessor comple, Xenopus/Amphibian, subunit DGCR8; DiGeorge syndrome critical region 8; DGCR8; C22orf12; DGCRK6