Home  >  Products  >  Dipeptidyl Peptidase 10 (Dipeptidyl-peptidase 10, DPP10, Dipeptidyl Peptidase X, DPP X, Inactive Dipeptidyl Peptidase 10, Dipeptidyl Peptidase IV-related Protein 3, DPRP3, DPRP-3, Dipeptidyl Peptidase-like Protein 2, DPL2, DPPY, KIAA1492)
Dipeptidyl Peptidase 10 (Dipeptidyl-peptidase 10, DPP10, Dipeptidyl Peptidase X, DPP X, Inactive Dipeptidyl Peptidase 10, Dipeptidyl Peptidase IV-related Protein 3, DPRP3, DPRP-3, Dipeptidyl Peptidase-like Protein 2, DPL2, DPPY, KIAA1492)

Dipeptidyl Peptidase 10 (Dipeptidyl-peptidase 10, DPP10, Dipeptidyl Peptidase X, DPP X, Inactive Dipeptidyl Peptidase 10, Dipeptidyl Peptidase IV-related Protein 3, DPRP3, DPRP-3, Dipeptidyl Peptidase-like Protein 2, DPL2, DPPY, KIAA1492)

Cat no: D8065-32M

Supplier: United States Biological
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DPL2 (DPP10), a novel 796-amino-acid protein, with significant sequence identity to DPP4 (32%) and DPP6 (51%) respectively. is a member of the dipeptidyl peptidase IV (DPIV) gene family. DPL2 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. The DPP10 gene is located on the long arm of chromosome 2 (2q12.3-2q14.2). Alternate transcriptional splice variants, encoding different isoforms, DPL2-s, DPL2-l have been characterized. DPL2 mRNA is expressed mainly in the Human brain and pancreas. DPL2 lacks active-site serine residue being replaced by a glycine residue required to confer dipeptidyl peptidase activity and has instead evolved features that enable it to act as an important component of voltage-gated potassium channels. Mutations in DPL2 gene have been associated with asthma. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 20ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Brain, Neurons Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D8065-32M
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Dipeptidyl-peptidase 10 (Non-functional)
Additional info: Recognizes human DPP10.

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