DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457)

Cat no: D8066-83E

Supplier: United States Biological

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The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE- like (NUDEL) and phosphodiesterase 4B. DISC1 has been associated with the risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression and Asperger syndrome. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Brain (Hippocampus) lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	D8066-83E
Reactivities:	Human
Hosts:	Goat
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes human DISC1.

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DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457)

Cat no: D8066-83E

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