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Dkk-1 (DKK1, SK, DKK-1, Dickkopf Homolog 1 (Xenopus laevis), Dickkopf-1 Like, Dickkopf (Xenopus laevis) Homolog 1)

Cat no: D3810

Dkk-1 (DKK1, SK, DKK-1, Dickkopf Homolog 1 (Xenopus laevis), Dickkopf-1 Like, Dickkopf (Xenopus laevis) Homolog 1)

The human Dickkopf (Dkk)-related proteins are a structurally and functionally heterogeneous family of proteins. This family is comprised of hDkk1, -2, -3, -4 and Soggy (Sgy), a Dkk-3 related protein. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues and are secreted when expressed in 293T cells. Several secreted antagonists, including Dickkopf-1 (Dkk-1) (German for

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SPECIFICATIONS

Catalog Number

D3810

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.

P Type

Pab

Purity

Purified by epitope affinity chromatography.

Isotype

IgG

References

1. Krupnik VE, et al. Gene 238(2):301-313, 1999.2. Niehrs C, et al. Int J Dev Biol 45(1):237-240, 2001.3. Glinka A, et al. Nature 391(6665):357-362, 1998.4. Fedi P, et al. J Biol Chem 274(27):19465-19472, 1999.5. Balfico A, et al. Nat Cell Biol 3(7):683-686, 2001.6. Semenov MV, et alCurr Biol 11(12):951-961, 2001.7. Grotewold L & Ruther U. Int J Dev Biol 46(7):943-947, 2002a.8. Grotewold L & Ruther U. EMBO J 21(5):966-975, 2002b.9. Shou J, et al. Oncogene 21(6):878-889, 2002.

Additional Info

Recognizes human and mouse Dkk-1 proteins. On Western blots, it identifies the target band at ~35kD. Reactivity has been confirmed with human Dkk-1-transfected 293T cell lysates.

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Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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