DLGAP1 (pan-SAPAP, DAP-1, Disks large-associated protein 1, Gkap, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, rGKAP, SAP90/PSD-95-associated protein 1, SAPAP1)

SAPAP1 is a member of the SAPAP family of proteins and is thought to be instrumental in the postsynaptic scaffold of neurons. SAPAP1 may function to assemble various other proteins at synapses. These functional proteins include scaffolding proteins, signaling proteins and cytoskeletal proteins. SAPAP1 is primarily found in the brain and more specifically in the cell body zones.\n\nApplications:\nSuitable for use in Western Blot, Immunofluorescence and Immunohistochemistry. Other applications have not been tested. \n\nRecommended Dilutions: \nWestern Blot: 2ug/ml detects SAPAP on 10ug of rat brain membrane tissue lysate.\nImmunohistochemistry: 1:400 detects SAPAP in rat schwan cells (putamen area) and rat dopaminergic neurons.\nImmunofluorescence: used in cultured rat hippocampal pyramidal cells and interneurons.\nOptimal dilutions to be determined by the researcher. \n\nPositive Control: \nRat brain membrane tissue lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

D3799-15A

Size

100ug

Applications

IF, IHC, WB

Hosts

Mouse

Reactivities

Rat

Form

Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide.

P Type

Mab

Purity

Purified by protein G affinity chroamtography.

Isotype

IgG2b,k

Additional Info

Recognizes rat pan-SAPAP (DLGAP1).

Alternative Names

discs, large (Drosophila) homolog-associated protein 1\nSAP90/PSD-95-associated protein 1\ndisks large-associated protein 1\nGuanylate kinase-associated protein\nPSD-95/SAP90 binding protein 1\nPSD-95/SAP90-binding protein 1