Home  >  Products  >  DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, Mitochondrial, Dihydrolipoamide Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, E2, E2K, DLTS)
DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, Mitochondrial, Dihydrolipoamide Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, E2, E2K, DLTS)

DLST (Dihydrolipoyllysine-residue Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, Mitochondrial, Dihydrolipoamide Succinyltransferase Component Of 2-oxoglutarate Dehydrogenase Complex, E2, E2K, DLTS)

Cat no: D7800-20C

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Alpha-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in mitochondria (1). Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2). Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1). Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2). Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D7800-20C
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, 50% glycerol.
P type: Pab
Purity: Purified by Protein A affinity chromatography.
References: 1.Ohta, S. and Ohsawa, I. (2006) J Alzheimers Dis 9, 155-66. 2.Dumont, M. et al. (2009) Free Radic Biol Med 47, 1019-27.
Additional info: Recognizes endogenous levels of total human DLST. Species Crossreactivity: Monkey, mouse and rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave